The Effect of Aerobic Exercise with Two Different Intensities on Changes Selected Biomarkers of myocard injury (CK-MB and cTnI) in Non- athletes Middle-Aged Men

Mohayyer Giglou, Azimeh and Bolboli, Lotfali and Nakhostin Roohi, Babak (2016) The Effect of Aerobic Exercise with Two Different Intensities on Changes Selected Biomarkers of myocard injury (CK-MB and cTnI) in Non- athletes Middle-Aged Men. Masters thesis, University of Mohaghegh Ardabili.

Text (تاثیر یک وهله تمرین هوازی با دو شدت‌ متفاوت بر تغییرات شاخص های منتخب آسیب میوکارد (CK-MB و cTnI) در مردان میانسال غیر ورزشکار) Azimeh Mohayyer Giglou.pdf Download (1MB)

Abstract

Aim: Cardiac biomarkers are factors that are used in the diagnosis of heart tissue damage and acute myocardial infarction. The aim of this study was to evaluate the effects of aerobic exercise with two different intensities on selected biomarkers of myocardium injury (cTnI and CK-MB) in non- athletes middle-aged males. Methods: Sixteen healthy non- athletes middle-aged males ( with a mean age 71/6 ± 20/41 years, height 77/5 ± 96/176 cm and weight 17/8 ± 07/74 kg) were randomly selected.. and participated in the study in crossover design with 14 day wash out. Then, they. were randomly assigned to one of two groups (Group A:8 and Group B: 8). In the first phase, group A ran on treadmill with 60% maximum oxygen consumption (moderate intensity) and the group B with 75% of maximum oxygen consumption )high intensity (for 30 minutes. After wash out, in the second phase, group A ran with 75% of maximum oxygen consumption and group B with 60% maximum oxygen consumption for 30 minutes. Blood samples were taken before, immediately after, and 4 hours after exercise.Result: According to data, immediately after the both groups, did not troponin I (cTnI) significantly increase (P>0.46). However, four hours after exercise cTnI was significantly increased (P<0.001) . 75% of maximum oxygen consumption compared with 60% of maximum oxygen consumption (P<0.001).CK-MB iso¬¬¬enzyme significantly increased in both groups immediately after exercise (P<0.001), four hours after exercise there was significant differences between two groups (P<0.03) .Conclusion: The results of this study indicate 30 min exercise with 60% and 75% of maximum oxygen consumption can increase cTnI and CK-MB in non- athletes healthy meadle-aged males CTnI significantly increase in the group who trained with high intensity Therefore, the myocardium inkury is signifivantly lower who trained with moderate intensity. Keywords: Myocardial injury, CTnI, CK-MB, Acute Aerobic Exercise

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