The effect of airobic exercise with intensity 70% of VO 2max on hematopoietic stem cells CD34+ and it is relationship with lipid profile in middle aged men

Mamashli, Eahe and Siahkouhian, Marefat and Bolboli, Lotfali (2015) The effect of airobic exercise with intensity 70% of VO 2max on hematopoietic stem cells CD34+ and it is relationship with lipid profile in middle aged men. Masters thesis, university of Mohaghegh Ardabili.

Text (ارزیابی اثر یک وهله تمرین هوازی با شدت 70 درصد حداکثر اکسیژن مصرفی بر سلول¬های بنیادی خونسازCD34+ و ارتباط آن با نیمرخ لیپیدی در مردان میانسال شهرستان اردبیل) Eahe Mamashli.pdf Download (1MB)

Abstract

The purpose of this study was to evaluate the effect of aerobic exercise training with the 70% Vo2max on hematopoietic stem cells CD34+ mobilization and it is relationship with lipid profile in middle aged men. Methods: For this purpose, 16 middle aged men (age 52.25±3.04 yrs, weight 82.09 ± 8.12 kg and BMI 28.14±2.60 kg/m2) in the study were volunteers and randomly divided into 2 groups (control N: 8, the experimental group N: 8) experimental group ran for 30 minutes with 70% of VO2max on the treadmill. blood samples were taken from all subjects for measurement of hematopoietic stem cells CD34+ and Isotype control and lipid profile befor and 10 minutes after the test protocol. The paired- samples T Test were used for comparisons within a group. To compare variation between the groups were used independent sample T Test and to determine the relationship between variables Pearson correlation coefficient. Statistical significance was accepted as p ≤ 0.05. Result: physical activity with the 70% Vo2max significantly increased the number of CD34+ cell, with 14 percent (P =0.002), but no significant difference was observed between the training group and the control group no significant change in the pre-test and post-test (P= 0.082). Between CD34+ and LDL / HDL ratio and Chol / HDL relationship was not significant. Conclusion:aerobic exercise training with intensity 70 % of Vo2max can significantly increased CD34+ cell circulating in the peripheral blood and because of the potential role of these cells in angiogenesis and neo vasculogenesis help to repair and regeneration vessels. Inverse relationship between serum lipid levels (as a risk factor for cardiovascular disease) and CD34+ cell if approved will be used as a predictor of cardiovascular disease will be presented.

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